1000 s state: South Loop Luxury Apartments – Chicago Apartments
Luxury Apartment Amenities | 1000 South Clark
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43,000 Square Feet of Amenities
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Enjoy Everything South Clark Has to Offer
FITNESS
- 10,000 square foot gym
- Basketball Court
- Pickleball Court
- Outdoor Track
- Sauna
SUNBATHE & SWIM
- Year-Round Pool
- Outdoor Jacuzzi
- Expansive Sundeck
- Outdoor Lounge with TV’s
- Outdoor Lounge with Firepits
PET PAMPERINGS
- On-Site Doggie Daycare
- Outdoor Dog Run
- Dog Walking
- In-Home Cat Care
- Boarding
- Pet Spa
SERVICES
- On-site Dry Cleaner
- Minte Housecleaning
- Pearchef Room Service
- Guest Suite
- Secured Heated Bike Storage
ROOFTOP RESPITE
- Skyview Lounge
- Rooftop Terrace
- Outdoor Lounge with Firepits
INDULGE & IMBIBE
- Wine Lounge
- Neighborhood Bar
EAT & ENTERTAIN
- Demonstration Kitchen
- Outdoor Grilling Stations
- Billiards Lounge
- Game Room
BUSINESS CENTER
- Newsroom
- Boardroom
- Printing Station
- Co-Working Room
10,000
Square Foot
Fitness Facility
Get fit with a 1/6-mile outdoor running track, separate Fitness On Demand rooms, pickleball and basketball courts, and year-round pool.
Check It Out
Redefine Your Expectations Of An On-Site Fitness Center
SPORTS COURTS
- Basketball
- Pickleball
STRENGTH
- Racks + Machines
- Kettlebells & Weights
CARDIO
- Treadmills + Ellipticals
- Full Cycling Studio
GROUP SUITE
- On-Demand Classes
- Full Yoga Studio
CLUB COMFORTS
- Lockers & Sauna
- 1/6 Mile Outdoor Track
On-Site Pet Care
DOG. Hotel | Daycare offers superior pet care services, right outside of your front door. Whether you have an active pup who loves being around friends at doggie daycare, or if they prefer to go solo with private walks, DOG. Hotel | Daycare caters to any pet’s personality. With a full-service grooming, group training classes, cat sitting services and exclusive rates for residents of 1000 South Clark – you won’t find another South Loop community with an amenity quite like this.
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Fireside Reading Room &
Climate-Controlled Wine Storage
This room is a cozy setting featuring a fireplace, wine fridge, and comfortable seating where you can enjoy your favorite book or glass of wine (though we prefer both). For events with a crew, it makes the perfect place to host a wine or book club event, or play board games with friends.
Video Tour of Our Library & Wine Bar
Keg Taps, Full-Length Bar,
Arcade Games & Big Screen TV’s
The Neighborhood Bar Lounge is the perfect spot to meet up with friends to watch your favorite sporting evenet. The lounge is fully equipped with a BYO tap & sleek bar fridge, three televisions, a foosball table, and two retro arcade games. Better yet, this room is available for private rental and parties.
Video Tour of Our Neighborhood Beer Bar
Sprawling Sundeck with Dining, Tanning,
and Outdoor Firepits, Bars, & Grills
Our 20,000 SF sundeck provides ample space for entertaining. Lay out on a lounge chair, spark up a stainless steel grill, or turn on the Outdoor TVs to watch the game with the skyline in-view and the firepits ablaze.
Video Tour of Our Rooftop Sundeck
Restaurant-Quality Kitchen with
Adjacent Dining Suite for Entertaining
Video Tour of Our Restaurant Kitchen
Billiards Lounge & Casino Game Room
with Cards Table, Arcade Games, & TV
Video Tour of Our Billiards Lounge
10,000 SF Fitness Facility with Benches,
Racks, Weights, Cardio, & Cycling Studio
Video Tour of Our Fitness Facility
Hardwood Basketball Court with
Plug & Play Surround Sound System
Video Tour of Our Basketball Court
All-Weather Swimming Pool with
Outdoor Jacuzzi & Tanning Deck
Video Tour of Our Pool & Jacuzzi
ASK ABOUT OUR SPECIALS! For more information about leasing, please email us at [email protected].
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1001 S. State – Apartments in Chicago South Loop
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South Loop Luxury Apartments
When it comes to innovative rental living apartments in Chicago’s South Loop area, 1001 South State offers excellent options for people who want to combine luxury with accessibility to all the best nearby locations. Not only do you get to live in a unique building with comfortable units, the amenities at this rental community truly offer something unique close to Columbia College, Depaul University, and the Art Institute. Careful attention was used to create an ideal space for your unique lifestyle needs.
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South Loop High-Rise Comfort in Chicago
Choose from a studio, one, two, or three-bedroom apartment at 1001 South State in Chicago. Everyone is carefully appointed with the most comfortable spaces, luxury materials, and custom designs that you should expect from a South Loop high-rise community of this caliber. The various floor plans give you the opportunity to arrange your living space precisely how it suits your needs. The floor to ceiling windows present glorious views of Chicago at large.
Besides exceptional apartment spaces, the community offers a wide variety of shared amenities to all residents. Take a dip in the pool, visit the fitness center or yoga studio, share eco-friendly bikes, let your dog run in the safe space, and take time to relax in the herb garden or around a cozy fire pit.
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South Loop rentals put you in the center of amazing dining, shopping, and lifestyle opportunities. Pick up your groceries at Trader Joe’s, visit the nearby Shred 45 or Orange Theory Fitness places, had to Target for housewares or enjoy local dining favorites that offer sushi, waffles, fine Italian dining, cocktails and draft beers, and so much more. Do not forget Soldier Field, Millennium Park, the Adler Planetarium or Shedd Aquarium for unique excursions.
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General and specific IgE. Diseases and conditions accompanied by changes in the content of total IgE
- INVITRO org/ListItem”> Library
- Laboratory …
- General and specific …
Allergy
Helminths
Worms
Rhinitis
Urticaria
Ataxia
4360
12 October
Immunoglobulin E (IgE) is a class of immunoglobulins found normally in small amounts in blood serum and secretions. IgE was isolated for the first time in 1960s from the sera of patients with atopy and multiple myeloma. In 1968, WHO identified IgE as an independent class of immunoglobulins. According to WHO, 1 IU / ml (IU – international unit) corresponds to 2.4 ng. Usually the concentration of IgE is expressed in IU / ml or kU / l (kU – kilounit).
Normally, IgE is less than 0.001% of all serum immunoglobulins (see Table 1).
Table 1: The content of IgE in the blood serum of healthy people
Age groups | IgE (ke/l) |
---|---|
Up to 1 year | 0 – 15 |
1 year-6 years | 0 – 60 |
6 -10 years | 0 – 90 |
10 -16 years old | 0 – 200 |
adults | 0 – 100 |
The structure of IgE is similar to that of other immunoglobulins and consists of two heavy and two light polypeptide chains. They are grouped into complexes called domains. Each domain contains approximately 110 amino acids. IgE has five such domains, in contrast to IgG, which has only four. According to the physicochemical properties, IgE is a glycoprotein with a molecular weight of approximately 1
daltons, consisting of 12% carbohydrates. IgE has the shortest lifespan (half-life from blood serum 2-3 days), the highest rate of catabolism and the lowest rate of synthesis of all immunoglobulins (2.3 µg/kg per day). IgE is synthesized mainly by plasma cells localized in the mucous membranes. The main biological role of IgE is the unique ability to bind to the surface of human mast cells and basophils. On the surface of one basophil there are approximately 40,000 – 100,000 receptors that bind from 5,000 to 40,000 IgE molecules.
Degranulation of mast cells and basophils occurs when two IgE molecules associated with the cell membrane bind to an antigen, which in turn “turns on” successive events leading to the release of inflammatory mediators.
In addition to being involved in type I (immediate) allergic reactions, IgE is involved in protective helminthic immunity, which is due to the existence of cross-linking between IgE and the helminth antigen. The latter penetrates the mucosal membrane and sits on mast cells, causing their degranulation. Inflammatory mediators increase capillary and mucosal permeability, resulting in IgG and leukocytes leaving the bloodstream. IgG-coated helminths are joined by eosinophils, which eject the contents of their granules and thus kill the helminths.
IgE can be detected in the human body as early as the 11th week of fetal development. The content of IgE in the blood serum increases gradually from the moment of birth of a person until adolescence. IgE levels may decrease with age.
In the practice of clinical diagnostic laboratories, the determination of general and specific IgE is carried out in order to use them as independent diagnostic indicators. In table. 2 lists the main diseases and conditions accompanied by a change in the content of total IgE in blood serum.
Table 2: Diseases and conditions associated with changes in total serum IgE
Diseases and conditions | Possible reasons |
I. Increased content of IgE | |
---|---|
Allergic diseases due to IgE antibodies: a) Atopic diseases Allergic rhinitis · Atopic bronchial asthma Atopic dermatitis Allergic gastroenteropathy b) Anaphylactic diseases Systemic anaphylaxis Urticaria – angioedema |
Multiple allergens: pollen dust epidermal food medicinal preparations chemicals metals foreign protein |
Allergic bronchopulmonary aspergillosis | Unknown |
Helminthiases | IgE antibodies associated with protective immunity |
Hyper-IgE syndrome (Job’s syndrome) | T-suppressor defect |
Selective IgA deficiency | T-suppressor defect |
Wiskott-Aldridge Syndrome | Unknown |
Thymus aplasia (DiGeorge syndrome) | Unknown |
IgE – myeloma | IgE-producing plasma cell neoplasia |
graft-versus-host disease | T-suppressor defect |
II. Decreased total IgE | |
Ataxia – telangiectasia | T cell defects |
Below are given as examples the ranges of total IgE serum levels (in adults) in some pathological conditions (Table 3). However, despite the initial apparent ease of using the determination of total and specific IgE for diagnosis, there are some difficulties in interpreting the results. Their list is given below.
Table 3: Total IgE values in some pathological conditions
Pathological conditions | IgE content (ke/l) |
---|---|
allergic rhinitis | 120 – 1000 kU/l |
Atopic bronchial asthma | 120 – 1200 kU/l |
Atopic dermatitis | 80 – 14000 kU/l |
Allergic bronchopulmonary aspergillosis: – remission – aggravation |
80 – 1000 kU/l 1000 – 8000 kU/l |
Hyper – IgE syndrome | 1000 – 14000 kU/l |
IgE – myeloma | 15000 kU/l and above |
Features of interpretation and diagnostic limitations of total IgE
- Approximately 30% of patients with atopic diseases have a level of total IgE within the normal range.
- Some people with asthma may have hypersensitivity to only one allergen (antigen), resulting in total IgE being in the normal range, while skin testing and specific IgE will be positive.
- The concentration of total IgE in the blood serum also increases in non-atopic conditions (especially with helminthic invasion, some forms of immunodeficiency and bronchopulmonary aspergillosis) with subsequent normalization after appropriate treatment.
- Chronic recurrent urticaria and angioedema are not mandatory indications for the determination of total IgE, as they are usually non-immune in nature.
- The normal limits defined for Europeans cannot be applied to representatives of areas endemic for helminthiases.
Features of interpretation and diagnostic limitations of specific IgE
- Availability of specific IgE determination should not exaggerate its diagnostic role in the examination of patients with allergies.
- Detection of allergen-specific IgE (to any allergen or antigen) does not prove that this particular allergen is responsible for clinical symptoms; the final conclusion and interpretation of laboratory data should be made only after comparison with the clinical picture and the data of a detailed allergic history.
- The absence of specific IgE in peripheral blood serum does not exclude the possibility of an IgE-dependent mechanism, since local IgE synthesis and mast cell sensitization can occur in the absence of specific IgE in the bloodstream (for example, allergic rhinitis).
- Antibodies of other classes specific for this allergen, especially the class IgG (IgG4), may cause false negative results.
- Exceptionally high concentrations of total IgE, for example, in individual patients with atopic dermatitis, may, due to non-specific binding to the allergen, give false positive results.
- Identical results for different allergens do not imply the same clinical significance, since the ability to bind to IgE in different allergens may be different.
Table 4: Indications and contraindications for specific IgE testing
Indications | |
---|---|
1 | Differential diagnosis between IgE-dependent and non-IgE-dependent mechanisms of allergic reactions |
2 | Patients in whom it is impossible to identify the allergen by anamnestic history, using a diary, etc. |
3 | Patients with insufficient effect of specific hyposensitization prescribed based on the results of skin tests |
4 | Dermographism and widespread dermatitis |
5 | Patients of childhood and the elderly with skin hyporeactivity |
6 | Skin hyperreactivity |
7 | Patients who cannot stop symptomatic therapy with drugs that affect the results of skin tests |
8 | Negative attitude of the patient to skin tests |
9 | History of systemic allergic reactions to skin tests |
10 | Inconsistency of the results of skin tests with the data of the anamnesis and the clinical picture |
eleven | IgE-dependent food allergy |
12 | The need to quantify the sensitivity and specificity of the allergen |
13 | Total IgE of blood serum more than 100 kU/l |
Examination is inappropriate: | |
1 | In atopic diseases in cases of satisfactory results of specific therapy according to skin tests |
2 | In patients with a non-IgE-dependent mechanism of an allergic reaction |
Related links: Immunoglobulin E, IgE general (allergodiagnostics), allergen panels.
Sources:
- Macharadze D.Sh. Modern clinical aspects of assessing the levels of general and specific IgE // Pediatrics. 2017; 96(2): 121-127.
- Rybnikova E.A., Prodeus A.P., Fedoskova T.G. Modern approaches to the laboratory diagnosis of allergies – to help the practitioner // BC. Medical review. – No. 1 of 04/26/2021. – pp. 43-49. DOI: 10.32364/2587-6821-2021-5-1-43-49
IMPORTANT!
The information in this section should not be used for self-diagnosis or self-treatment. In case of pain or other exacerbation of the disease, only the attending physician should prescribe diagnostic tests. For diagnosis and proper treatment, you should contact your doctor.
For a correct assessment of the results of your analyzes over time, it is preferable to do studies in the same laboratory, since different laboratories may use different research methods and units of measurement to perform the same analysis.
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aggregate state of matter – article – Corporation Russian textbook (Drofa-Ventana publishing house)
State of aggregation – the state of any substance that has certain properties : the ability to maintain shape and volume, to have a long-range or short-range order, and others. When the state of aggregation of a substance changes, the physical properties, as well as the density, entropy and free energy, change.
How and why do these amazing transformations take place? To understand this, let’s remember that everything around consists of atoms and molecules . Atoms and molecules of various substances interact with each other, and it is the connection between them that determines the state of aggregation of a substance.
There are four types of aggregate substances:
-
gaseous,
-
liquid,
-
hard,
-
plasma.
It seems that chemistry reveals its secrets to us in these amazing transformations. However, it is not. The transition from one state of aggregation to another, as well as Brownian motion or diffusion, are physical phenomena, since in these transformations there are no changes in the molecules of the substance and their chemical composition is preserved.
Gaseous state
At the molecular level, a gas is a randomly moving, colliding with the walls of the vessel and with each other, molecules that practically do not interact with each other. Since the gas molecules are not connected to each other, the gas fills the entire volume provided to it, interacting and changing direction only when they hit each other.
Unfortunately, it is impossible to see gas molecules with the naked eye and even with a light microscope. However, the gas can be touched. Of course, if you just try to catch gas molecules flying around in your palm, then you will not succeed. But surely everyone saw (or did it themselves) how someone inflated the tire of a car or bicycle with air, and from soft and wrinkled it became inflated and elastic. And the apparent “weightlessness” of gases will refute the experiment described on page 39textbook “Chemistry Grade 7” edited by O.S. Gabrielyan.
This happens because a large number of molecules get into the closed limited volume of the tire, which become crowded, and they begin to hit each other and the tire walls more often, and as a result, the total effect of millions of molecules on the walls is perceived by us as pressure.
But if the gas occupies the entire volume provided to it, , why then does it not fly away into space and spread throughout the universe, filling interstellar space? So, something still retains and limits gases by the atmosphere of the planet?
Quite right. And this is the force of gravity . In order to break away from the planet and fly away, the molecules need to develop a speed exceeding the “escape speed” or the second cosmic velocity, and the vast majority of molecules move much more slowly.
Then the following question arises: Why do gas molecules do not fall to the ground, but continue to fly? It turns out that thanks to solar energy, air molecules have a solid supply of kinetic energy, which allows them to move against the forces of gravity.
Liquid state
By increasing the pressure and/or decreasing the temperature, gases can be converted into a liquid state. As early as the dawn of the 19th century, the English physicist and chemist Michael Faraday succeeded in converting chlorine and carbon dioxide into a liquid state by compressing them at very low temperatures. However, some of the gases did not succumb to scientists at that time, and, as it turned out, it was not a lack of pressure, but an inability to reduce the temperature to the required minimum.
A liquid, unlike a gas, occupies a certain volume, but it also takes the form of a filled vessel below the surface. Visually, the liquid can be represented as round beads or cereals in a jar. Liquid molecules are in close interaction with each other, but freely move relative to each other.
If a drop of water remains on the surface, after a while it will disappear. But we remember that thanks to the law of conservation of mass-energy, nothing disappears and does not disappear without a trace. The liquid will evaporate, i.e. will change its state of aggregation to gaseous.
Evaporation – is the process of transformation of the aggregate state of matter, in which molecules whose kinetic energy exceeds the potential energy of intermolecular interaction rise from the surface of a liquid or solid .
Evaporation from the surface of solids is called sublimation or sublimation . The easiest way to observe sublimation is to use naphthalene to fight moths. If you smell a liquid or a solid, then evaporation is occurring. After all, the nose captures the fragrant molecules of the substance.
Liquids surround a person everywhere. The properties of liquids are also familiar to everyone – this is viscosity, fluidity. When talking about the shape of a liquid, many people say that the liquid has no definite shape. But this only happens on Earth. Due to the force of gravity, a drop of water is deformed.
However, many have seen astronauts catching water balloons of various sizes in zero gravity. In the absence of gravity, the liquid takes the form of a ball. And the force of surface tension provides the liquid with a spherical shape. Soap bubbles are a great way to get acquainted with the force of surface tension on the Earth.
Another property of a liquid is viscosity. Viscosity depends on pressure, chemical composition and temperature. Most liquids obey Newton’s law of viscosity, discovered in the 19th century. However, there are a number of liquids with high viscosity, which under certain conditions begin to behave like solids and do not obey Newton’s law of viscosity. Such solutions are called non-Newtonian fluids. The simplest example of a non-Newtonian fluid is a suspension of starch in water. If you act on a non-Newtonian fluid with mechanical forces, the fluid will begin to take on the properties of solids and behave like a solid.
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Solid State
If in a liquid, unlike a gas, molecules no longer move randomly, but around certain centers, then in a solid state of aggregation of matter, atoms and molecules have a clear structure and look like lined up soldiers in a parade. And thanks to the crystal lattice, solids occupy a certain volume and have a constant shape.
Between solid and liquid bodies, there is an intermediate group of amorphous substances, whose representatives, on the one hand, retain their shape for a long time due to their high viscosity, and on the other hand, the particles in it are not strictly ordered and are in a special condensed state. Amorphous substances include a number of substances: resin, glass, amber, rubber, polyethylene, polyvinyl chloride, polymers, sealing wax, various adhesives, ebonite and plastics. You can read in detail about amorphous bodies on page 40 of the textbook “Chemistry Grade 7” edited by O.S. Gabrielyan.
Under certain conditions, substances that are in the aggregate state of a liquid can turn into a solid, and solids, on the contrary, when heated, melt and turn into a liquid.
This is because when heated, the internal energy increases, respectively, the molecules begin to move faster, and when the melting point is reached, the crystal lattice begins to break down and the state of aggregation of the substance changes. For most crystalline bodies, the volume increases during melting, but there are exceptions, for example, ice, cast iron.
Depending on the type of particles that form the crystal lattice of a solid, the following structure is distinguished:
-
molecular
-
nuclear,
-
ionic
-
metal.
For some substances, the change in aggregate states occurs easily, as, for example, for water, for other substances, special conditions (pressure, temperature) are needed. But in modern physics, scientists distinguish one more independent state of matter – plasma.
Plasma – ionized gas with the same density of both positive and negative charges . In wildlife, there is plasma in the sun, or in a lightning flash. The northern lights and even the familiar fire, which warms us with its warmth during a trip to nature, also refers to plasma.
Artificially created plasma adds brightness to any city. Neon advertising lights are just low-temperature plasma in glass tubes. Conventional fluorescent lamps are also filled with plasma.
Plasma is divided into low-temperature – with an ionization degree of about 1% and a temperature of up to 100 thousand degrees, and high-temperature – ionization of about 100% and a temperature of 100 million degrees (this is the state of plasma in stars).
Low-temperature plasma in fluorescent lamps familiar to us is widely used in everyday life.
High-temperature plasma is used in fusion reactions and scientists do not lose hope of using it as a replacement for atomic energy, but the control in these reactions is very difficult. And an uncontrolled thermonuclear reaction proved to be a weapon of colossal power when, on August 12, 1953 years the USSR tested a thermonuclear bomb.
To check the assimilation of the material, we offer a small test.
1. What does not apply to aggregate states:
-
liquid
-
gas
-
light +
2.